When I try to clear the cache and refresh the page via Ctrl+F5 (or just F5) I get the prompt Type the Internet address of a document, and Internet Explorer will open it for you with a drop down list in Internet Explorer. When I try F5 in Chrome and Firefox it opens the "Open file" dialog box.
When I try to F12 for Dev tools in Internet Explorer, Chrome & Firefox it opens up the print dialog box.
Why is this happening and what can I do to revert it back to the way it was?
You have a keyboard with an F-Lock key. The function lock is currently on. "Open file" and "Print" are the meanings of F5 and F12 when function lock is on.
So just turn it off.
Q894513 - Resolve unexpected Function (F1 - F12) or other special key behavior
. Microsoft KnowledgeBase.